About EB
Epidermolysis Bullosa, known as EB, is the name of a rare group of genetic skin disorders causing blistering and shearing of the skin from even the gentlest friction and sometimes spontaneously.
There are three major types of EB; Simplex, Dystrophic and Junctional. These vary from relatively mild to incapacitating, crippling, and sometimes fatal disorders. Within these there are over twenty different sub types of EB, each with their own characteristic symptoms.
All forms of EB are genetic in origin and the genes responsible for most of the sub-types of the condition are now known. Some still await identification.
The genetic defects result in the skin cells collapsing or skin layers not adhering properly to each other, causing areas of structural weakness. This fragile skin is particularly vulnerable to damage from friction, causing the continual blistering that is the characteristic feature of the condition.
To find out more about EB, take a look at our FAQs, Media Section and EB Publications Library




